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题名/责任者:

Molecular Basis for Mitochondrial Signaling edited by Tatiana K. Rostovtseva.

出版发行项:

Cham : Springer International Publishing : Imprint: Springer, 2017.

ISBN:

9783319555393

其它标准号:

10.1007/978-3-319-55539-3

载体形态项:

XIV, 386 p. 61 illus., 54 illus. in color. online resource.

主文献:

Springer eBooks

其他载体形态:

Printed edition: 9783319555379

丛编说明:

Biological and Medical Physics, Biomedical Engineering, 1618-7210

丛编统一题名:

Biological and Medical Physics, Biomedical Engineering,

附加个人名称:

Rostovtseva, Tatiana K. editor.

附加团体名称:

SpringerLink (Online service)

论题主题:

Physics.

论题主题:

Cell cycle.

论题主题:

Apoptosis.

论题主题:

Physics.

论题主题:

Biological and Medical Physics, Biophysics.

论题主题:

Cell Cycle Analysis.

论题主题:

Apoptosis.

中图法分类号:

Q24

内容附注:

From the Contents: Mitochondrial Calcium Signaling -- Systems approaches to mitochondrial calcium signaling -- The mitochondrial Calcium Uniporter: Molecular Composition And Physiological Role -- Molecular Mechanisms of Mitochondrial Ca2+ Uptake -- Ca2+ uniporter and male fertility.

摘要附注:

This book covers recent advances in the study of structure, function, and regulation of metabolite, protein and ion translocating channels, and transporters in mitochondria. A wide array of cutting-edge methods are covered, ranging from electrophysiology and cell biology to bioinformatics, as well as structural, systems, and computational biology. At last, the molecular identity of two important channels in the mitochondrial inner membrane, the mitochondrial calcium uniporter and the mitochondrial permeability transition pore have been established. After years of work on the physiology and structure of VDAC channels in the mitochondrial outer membrane, there have been multiple discoveries on VDAC permeation and regulation by cytosolic proteins. Recent breakthroughs in structural studies of the mitochondrial cholesterol translocator reveal a set of novel unexpected features and provide essential clues for defining therapeutic strategies. Molecular Basis for Mitochondrial Signaling covers these and many more recent studies of mitochondria function, their communication with other organelles, and their critical roles in development, aging, and in a plethora of stressful or degenerative events. Authored by leading researchers in the field, this volume will be an indispensable reference resource for graduate students and academics working in related areas of biophysics and cell biology as well as for professionals within industry.

电子资源:

http://dx.doi.org/10.1007/978-3-319-55539-3

豆瓣简介：